The Germanwings passenger jet crashed Tuesday in the French Alps region as it traveled from Barcelona to Dusseldorf, French officials.
Eric Ciotti, the head of the regional council, said search-and-rescue teams were headed to the crash site at Meolans-Revels.
The French newspaper La Provence, citing aviation officials, said the Airbus plane carried at least 142 passengers, two pilots and four flight attendants.